Pancreatic Cancer Research Matures

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Proteomics in Pancreatic Cancer Research

Pancreatic cancer is a highly aggressive malignancy with a poor prognosis and deeply affects the life of people. Therefore, the earlier diagnosis and better treatments are urgently needed. In recent years, the proteomic technologies are well established and growing rapidly and have been widely applied in clinical applications, especially in pancreatic cancer research. In this paper, we attempt ...

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Translational Research in Pancreatic Cancer

169: KRAS mutations in a population of patients operated for pancreatic adenocarcinoma [5] Researchers from Denmark presented a translational study on KRAS mutations in early pancreatic cancer. Previous reports had showed that the frequency of KRAS gene mutations in pancreatic cancer was as high as 75-90% [2]. This high percentage of KRAS mutations was representative of all pancreatic cancer st...

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Preclinical research in treatment of pancreatic cancer.

Pancreatic adenocarcinoma is an aggressive type of malignancy and remains a treatment-refractory cancer. Because of the few treatment options, understanding of the molecular mechanisms is necessary, for new drugs be developed against molecular targets. Two of the novel, promising regimens against molecular targets, NVP-BEZ235 and MSK-777, were examined in three preclinical studies performed in ...

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Top classic citations in pancreatic cancer research

BACKGROUND The number of times that articles are cited by is widely used to evaluate the impact of an article or an individual author has on its scientific community. This bibliometric analysis aimed to explore the top classic citations in pancreatic cancer (PC) research. METHODS A computerized literature search was conducted using the database, the Science Citation Index Expanded. The top 10...

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The CSCL field matures

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ژورنال

عنوان ژورنال: JNCI Journal of the National Cancer Institute

سال: 2007

ISSN: 0027-8874,1460-2105

DOI: 10.1093/jnci/djm180